Clinical trial · Observational
Predictors of Sorafenib Response in HCC
Predictors of Sorafenib Response in Patients With Advanced Hepatocellular Carcinoma
NCT05967429CI-TRIAL-00068381unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Evaluating the nutrition status of patients with advanced HCC who received sorafenib. Using the pretreatment nutrition status and quality of life as predictors to sorafenib response
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prognostic nutrition index | Diagnostic Test | — | UNRESOLVED |
| The neutrophil-to- lymphocyte ratio | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Hepatocellular carcinoma receiving sorafenib
- description
- Patient with advanced stage HCC receiving sorafenib
- interventionNames
- Diagnostic Test: The neutrophil-to- lymphocyte ratio
- Diagnostic Test: Prognostic nutrition index
Primary outcomes (3)
- measure
- assessment of nutrition status
- timeFrame
- Augest 2023 to March 2024
- description
- Prognostic nutrition index
- measure
- Predictors of sorafenib response
- timeFrame
- Augest 2023 to March 2024
- description
- The neutrophil-to- lymphocyte ratio
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * HCC recieved sorafenib Exclusion Criteria: * Patient refuse to participate * Patients recieving other treatment modalities
References
Publications (1)
- BACKGROUNDTakagi K, Buettner S, Ijzermans JNM. Prognostic significance of the controlling nutritional status (CONUT) score in patients with colorectal cancer: A systematic review and meta-analysis. Int J Surg. 2020 Jun;78:91-96. doi: 10.1016/j.ijsu.2020.04.046. Epub 2020 Apr 23. PMID 32335238