Clinical trial · Interventional
Real-Time CAD for Colonic Neoplasia: A RCT
Efficacy of Real-Time Computer Aided-Detected of Colonic Neoplasia in an Underserved Population, A Randomized Controlled Trial
NCT05963724CI-TRIAL-00068296CADcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study assesses the sensitivity and added benefits of computer-aided detection compared to standard care (white-light) in detecting colon polyps in patients undergoing colonoscopy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Real-Time Computer Aided Detection | Device | — | UNRESOLVED |
| Stanford Colonoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Real-Time Computer Aided Detection
- interventionNames
- Device: Real-Time Computer Aided Detection
- type
- ACTIVE_COMPARATOR
- label
- Standard Colonoscopy
- interventionNames
- Procedure: Stanford Colonoscopy
Primary outcomes (1)
- measure
- Adenoma Detection Rate
- timeFrame
- 1 year
Secondary outcomes (5)
- measure
- Adenomas Per Colon
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Undergoing colonoscopy at RUHS * Age \> 45 years * No contraindications to colonoscopy Exclusion Criteria: * Prior history of subtotal colectomy
References
Publications (2)
- BACKGROUNDThiruvengadam NR, Cote GA, Gupta S, Rodrigues M, Schneider Y, Arain MA, Solaimani P, Serrao S, Kochman ML, Saumoy M. An Evaluation of Critical Factors for the Cost-Effectiveness of Real-Time Computer-Aided Detection: Sensitivity and Threshold Analyses Using a Microsimulation Model. Gastroenterology. 2023 May;164(6):906-920. doi: 10.1053/j.gastro.2023.01.027. Epub 2023 Feb 2. PMID 36736437
- DERIVEDThiruvengadam NR, Solaimani P, Shrestha M, Buller S, Carson R, Reyes-Garcia B, Gnass RD, Wang B, Albasha N, Leonor P, Saumoy M, Coimbra R, Tabuenca A, Srikureja W, Serrao S. The Efficacy of Real-time Computer-aided Detection of Colonic Neoplasia in Community Practice: A Pragmatic Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2024 Nov;22(11):2221-2230.e15. doi: 10.1016/j.cgh.2024.02.021. Epub 2024 Mar 2. PMID 38437999