Clinical trial · Observational
Cardiac Management of Patients With Thalassemia Minor and Breast Cancer
Management of Patients With Thalassemia Minor and Breast Cancer at CardioOncology Outpatient Clinics: Age Quod Agis (AQUA)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This retrospective study aimed to evaluate the demographic characteristics, clinical conditions in term of physical examination findings), functional status, and laboratory results of patients with thalassemia minor (TM) and breast cancer (BC) in order to identify any differences between the group with BC only. Available data as anticancer treatment, comorbidities, weight and height will be combined to report body mass index (BMI) in kg/m2, systolic and diastolic blood pressure, heart rate, ECG, transthoracic echocardiography, blood count, lipid panels, glucose, kidney function tests, (N terminal) NT-proBNP, troponins, handgrip assessments, functional status were extracted from patients files and hospital electronic archives.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Heart Diseases | — | UNRESOLVED | — |
| Thalassemia Minor | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- 13 pts with BC+TM
- description
- Patients diagnosed with breast cancer and thalassemia minor
- label
- 13 pts with BC
- description
- Patients diagnosed with breast cancer for comparison.
Primary outcomes (3)
- measure
- Incidence of any rise in troponin
- timeFrame
- From enrollment to 12 months
- description
- Troponin results from baseline and at 3, 6 and 12 months of cancer treatment .
- measure
- Incidence of any rise in NT-ProBNP
- timeFrame
- From enrollment to 12 months
- description
- NT-ProBNP results from baseline and at 3, 6 and 12 months of cancer treatment .
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients with diagnosis of breast cancer, and thalassemia minor, 2. \>18 years old, 3. Referred by oncologist for cardiac evaluation. 4. Patients with available cardiac evaluations data at baseline and during breast cancer treatment Exclusion Criteria: 1. Patients without diagnosis of breast cancer, and thalassemia minor, 2. \<18 years old, 3. Patients without any cardiac evaluations at baseline, and during cancer treatment. 4. Patients with history of any cardiotoxic treatment prior to enrolment.
References
Publications (0)
Data not yet available