Clinical trial · Interventional
Evaluation of 3D Ultrasound in Brain Tumor Surgery
NCT05956977CI-TRIAL-00068222Neuro3DUSunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Evaluation of impact of use of 3D ultrasound in brain tumor surgery on extend of resection. Benefit for surgery, neurological outcome, accuracy and image quality are secondary outcome parameters. Control group is a retrospective matched pair cohort.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Residual Tumor | Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| resection with help of 3D ultrasound | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- prospective arm
- description
- Use of 3D ultrasound intraoperative before intraoperative MRI
- interventionNames
- Device: resection with help of 3D ultrasound
- type
- NO_INTERVENTION
- label
- retrospective matched pair arm
- description
- no use of intraoperative ultrasound before intraoperative MRI
Primary outcomes (1)
- measure
- Extent of resection
- timeFrame
- 48 hours after surgery
- description
- Volumetric assessment of residual T1 contrast enhancement or FLAIR signal changes in enhancing and non-enhancing glioma, respectively.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * age above 18 suspected intra-axial lesion (metastasis or Glioma) potential gross total resection of lesion Exclusion Criteria: * no ability for informed consent
References
Publications (1)
- RESULTAleo D, Elshaer Z, Pfnur A, Schuler PJ, Fontanella MM, Wirtz CR, Pala A, Coburger J. Evaluation of a Navigated 3D Ultrasound Integration for Brain Tumor Surgery: First Results of an Ongoing Prospective Study. Curr Oncol. 2022 Sep 15;29(9):6594-6609. doi: 10.3390/curroncol29090518. PMID 36135087