Clinical trial · Observational
A Study of Eribulin-Based Regimen Versus Other Chemotherpy in Triple-Negative Metastatic Breast Cancer (ERI-Based-01).
Efficacy and Safety of Eribulin-Based Regimen in the Treatment of Metastatic Triple-Negative Breast Cancer and Comparison With Other Chemotherapy Regimen: A Single-Center Retrospective Study
NCT05953909CI-TRIAL-00068146ERI-Based-01unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A Single-Center Retrospective Study About Efficacy and Safety of Eribulin-Based Regimen in the Treatment of Metastatic Triple-Negative Breast Cancer and Comparison With Other Chemotherapy Regimen
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Eribulin-Based Regimen | Drug | — | UNRESOLVED |
| nab-paclitaxel based regimen | Drug | — | UNRESOLVED |
| Other Chemotherapy Regimen | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Eribulin-Based Regimen
- description
- Not Applicable since observational study
- interventionNames
- Drug: Eribulin-Based Regimen
- Drug: nab-paclitaxel based regimen
- Drug: Other Chemotherapy Regimen
- label
- nab-paclitaxel based regimen
- description
- Not Applicable since observational study
- interventionNames
- Drug: Eribulin-Based Regimen
- Drug: nab-paclitaxel based regimen
- Drug: Other Chemotherapy Regimen
- label
- Other Chemotherapy Regimen
- description
- Not Applicable since observational study
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Women aged 18-70. 2. The pathologic diagnosis of unresectable recurrent or metastatic triple-negative breast cancer [ER-negative(IHC\<1%), PR-negative(IHC\<1%), HER2-negative(IHC-/+ or IHC++ and FISH/CISH-)]. 3. Eastern Cooperative Oncology Group (ECOG) performance status of ≤ 2. 4. Patients with at least one measuring lesion that was conformed to RECIST v1.1 standard. 5. Patients receiving eribulin-based therapy received at least two cycles of eribulin-based chemotherapy. Eribulin was treated until disease progression, unacceptable toxicity or patient refusal of treatment. 6. Adverse events were recorded according to the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE 5.0). Exclusion Criteria: 1. Patients previously treated with eribulin. 2. Patients with grade ≥3 adverse events did not recover according to CTCAE 5.0 criteria. 3. Not applicable to combined chemotherapy, or allergic or intolerant to related drugs.
References
Publications (0)
Data not yet available
No reference posted for this study.