Clinical trial · Interventional
Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana
Thibang Diphatlha: Testing Adaptive Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana
NCT05952141CI-TRIAL-00118891recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Investigators will test the effectiveness of adaptive strategies on timely adoption of cervical cancer treatment in Botswana using a pragmatic trial design.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Clinic Outreach | Behavioral | — | UNRESOLVED |
| Enhanced Outreach | Behavioral | — | UNRESOLVED |
| High-Touch Strategy | Behavioral | — | UNRESOLVED |
| Low-Touch Strategy | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Stage 1 Clinic Outreach + Stage 2 Low Touch
- description
- All participants receive direct clinic outreach to communicate readiness of results (stage 1). Participants who do not attend the clinic by 30 days (non-responders) will receive asynchronous text message reminders using framed messaging (stage 2).
- interventionNames
- Behavioral: Clinic Outreach
- Behavioral: Low-Touch Strategy
- type
- EXPERIMENTAL
- label
- Stage 1 Clinic Outreach + Stage 2 High Touch
- description
- All participants receive direct clinic outreach to communicate readiness of results (stage 1). Participants who do not attend the clinic by 30 days (non-responders) will receive asynchronous text message reminders using framed messaging in combination with synchronous patient navigation (stage 2).
- interventionNames
- Behavioral: Clinic Outreach
- Behavioral: High-Touch Strategy
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Patients will be eligible if they: 1. are biological females 2. are aged 18 or older 3. have pathology-confirmed invasive cervical cancer diagnosis 4. have pathology results evaluated at National Health Laboratory in Botswana 5. are citizens of Botswana 6. have no prior history of invasive cervical cancer Exclusion Criteria: Patients will be excluded if they: 1. are biological males or otherwise born without a cervix 2. are below the age of 18 due to the rarity of cervical cancer in this population 3. do not meet study inclusion criteria
References
Publications (1)
- DERIVEDRendle KA, Ramogola-Masire D, Grover S; Thibang Diphatlha Collective. Thibang Diphatlha: a sequential multiple assignment randomized trial designed to increase timely adoption of cervical cancer treatment in Botswana. Implement Sci Commun. 2024 Nov 12;5(1):128. doi: 10.1186/s43058-024-00659-9. PMID 39533437