Clinical trial · Interventional
Effects of CBT-Based Intervention Among Patients With Liver Cancer
Effects of Cognitive Behavioral Therapy-Based Intervention on Depression, Anxiety, Quality of Life, Immune Indicators, and Survival Among Patients With Liver Cancer
NCT05942560CI-TRIAL-00071621not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study investigates the effects of a CBT- based intervention on depression, anxiety, immune function, quality of life, and overall survival. It also explores if the effects of the intervention on immune function and quality of life are mediated through the improvements in depression and anxiety among patients with liver cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| CBT | — | UNRESOLVED | — |
| Depression | — | UNRESOLVED | — |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cognitive behavioural therapy-based intervention | Behavioral | — | UNRESOLVED |
| Educational group | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Cognitive behavioural therapy-based(CBT-based) intervention group
- description
- A specifically designed CBT-based intervention consisting of 8 weekly sessions will be conducted in a group format.
- interventionNames
- Behavioral: Cognitive behavioural therapy-based intervention
- type
- ACTIVE_COMPARATOR
- label
- Control group
- description
- Participants will receive eight health education sessions simultaneously with the CBT-based intervention group.
- interventionNames
- Behavioral: Educational group
Primary outcomes (8)
- measure
- Depression symptoms at baseline
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Adults (aged ≥18); 2. Diagnosed with liver cancer based on pathological findings or imaging findings in the medical record; 3. The severity level of depression and anxiety: Depression \> 7 using HAD-D, or Anxiety \> 7 using HAD-A (Hospital Anxiety and Depression Scale, HADS; HAD-D, Hospital Depression Scale; HAD-A, Hospital Anxiety Scale). Exclusion Criteria: 1. Patients who are taking part in another psychological intervention clinical trial or consented to receive another psychotherapy, suffered from aphasia and other communication difficulties will be excluded from the study 2. Patients with active immunological diseases, such as autoimmune diseases, and inflammatory diseases. 3. Patients accepting hormone therapy or taking long-term antibiotic drugs. 4. Patients who lack the basic ability of understanding and expression and are incompetent in giving consent.
References
Publications (0)
Data not yet available
No reference posted for this study.