Clinical trial · Interventional
Electroacupuncture for Chemotherapy-Related Cognitive Impairment
Electroacupuncture to Prevent Chemotherapy-Related Cognitive Impairment in Patients With Breast Cancer
NCT05941598CI-TRIAL-00068009unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this trial is to evaluate the effect of electroacupuncture compared to sham acupuncture in preventing CRCI among breast cancer patients scheduled to undergo chemotherapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chemotherapy-Related Cognitive Impairment | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Electroacupuncture | Device | — | UNRESOLVED |
| Sham acupuncture | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Electroacupuncture
- description
- After skin disinfection, acupuncture needles will be inserted into the acupoints. All needles will be manipulated to achieve deqi. Then, an electroacupuncture apparatus will be connected. The stimulation parameters will be continuous wave, 2 Hz, and the current intensity will be adjusted according to the participant's comfort level.
- interventionNames
- Device: Electroacupuncture
- type
- SHAM_COMPARATOR
- label
- Sham acupuncture
- description
- After skin disinfection, acupuncture needles will be inserted into acupoints that are unrelated to the treated syndromes. The needles will be inserted to a depth of 3 to 5 mm, without any manipulation or deqi. Then, the electronic acupuncture apparatus will be connected, with a continuous wave of 2 Hz. However, the intensity of electrical stimulation will be set to a minimum level that participants can perceive, and the apparatus will be turned off after 30 seconds of stimulation.
- interventionNames
- Device: Sham acupuncture
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Newly diagnosed with stage I-III breast cancer 2. Scheduled to undergo chemotherapy 3. Aged between 18 and 75 years 4. MoCA score ≥ 26 5. Voluntary agreement to participate in the study and sign an informed consent Exclusion Criteria: 1. Demonstrated tumor metastasis or recurrence 2. Had a prior history of chemotherapy 3. Reported a history of brain tumors, head trauma or stroke 4. Were diagnosed with cognitive function-impaired disorders, such as Alzheimer's disease 5. Were unable to cooperate with testing for any reasons 6. Had severe hepatic or renal insufficiency 7. Had hemorrhagic disorders, including von Willebrand disease, or were taking anticoagulant or antiplatelet medication 8. Had an implanted cardiac pacemaker 9. Had a history of alcohol abuse or drug addiction 10. Were participating in another interventional trial
References
Publications (0)
Data not yet available
No reference posted for this study.