Clinical trial · Observational
Fluorescence Imaging of the Parathyroid Glands of Children
Fluorescence Imaging for the Detection and Perfusion of the Parathyroid Glands of Children
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to develop a standardized and user-independent imaging workflow model for autofluorescence and quantified fluorescence angiography with Indocyanine Green (ICG) of the parathyroid glands of children. For this purpose, all pediatric patients will undergo thyroid surgery with the use of autofluorescence and quantified ICG-fluorescence. This study could be the first step in reducing the rate of postoperative hypocalcemia in children, by using fluorescence angiography during pediatric thyroid surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Thyroid Gland Carcinoma | Childhood Thyroid Gland Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Thyroid Diseases | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fluorescence imaging of the parathyroid glands of children | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Children (<18 years) that will undergo total thyroidectomy for any indication
- interventionNames
- Diagnostic Test: Fluorescence imaging of the parathyroid glands of children
Primary outcomes (3)
- measure
- Number and location of autofluorescent parathyroid glands
- timeFrame
- During thyroid surgery
- description
- Number and location of autofluorescent parathyroid glands
- measure
- Quantification of the fluorescent signal of ICG
- timeFrame
- During thyroid surgery
- description
- Quantification of the fluorescent signal of ICG
- measure
- Postoperative hypocalcemia
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients \<18 years 2. Patients undergoing total thyroidectomy (for any indication) 3. Patients undergoing lobectomy for the suspicion of a malignancy, with a subsequent completion thyroidectomy 4. Written informed consent (from parents/caregivers, patients or both, see chapter 6.0) Exclusion Criteria: 1. Patients with preoperative hypo - or hypercalcemia, treated for hypo- or hypercalcemia, (chronic) renal disease, kidney transplantation or any disorder that requires calcium supplementation (other than standard preoperative calcium supplementation for a total thyroidectomy). 2. Patients with known allergy to ICG or iodinated contrast 3. Pregnancy or breastfeeding 4. Patients with severe liver dysfunction 5. Preterm neonates 6. Newborn infants with an indication for exchange transfusion for severe neonatal hyperbilirubinemia
References
Publications (0)
Data not yet available