Clinical trial · Observational
Safety and Feasibility of Laparoscopic Intracorporeal Anastomosis for Colorectal Surgery- A Multiple Center Real World Study
NCT05911152CI-TRIAL-00067542SELECTEDunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to explore the safety and feasibility of laparoscopic intracorporeal anastomosis in colorectal cancer surgery. The main questions it aims to answer are: 1. If intracorporeal anastomosis is safe in terms of short-term outcome? 2. If intracorporeal anastomosis can achieve the same oncological outcome as conventional extracorporeal anastomosis?
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intracorporeal anastomosis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Intracorporeal anastomosis
- description
- Patients underwent laparoscopic colorectal surgery with intracorporeal anastomosis
- interventionNames
- Procedure: Intracorporeal anastomosis
- label
- Extracorporeal anastomosis
- description
- Patients underwent laparoscopic colorectal surgery with extracorporeal anastomosis
Primary outcomes (2)
- measure
- 3-year disease free survival
- timeFrame
- 3 year
- description
- Proportion of patients who remain alive without any signs or symptoms of disease recurrence or progression for a period of 3 years after surgery
- measure
- 3-year overall survival
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients voluntarily enrolled in this study and signed an informed consent form; 2. Age: 18-75 years; 3. Completion of colonoscopy and biopsy, with pathological confirmation of adenocarcinoma or high-grade intraepithelial neoplasia; 4. Preoperative enhanced CT or MRI examination showing no evidence of distant metastasis; 5. Preoperative staging as cT1-3NanyM0; 6. Underwent laparoscopic surgery. Exclusion Criteria: 1. Contraindications to laparoscopic surgery; 2. Cases requiring emergency surgery due to acute bowel obstruction, perforation, or bleeding; 3. Patients with distant metastasis; 4. Patients with multiple primary colorectal cancers; 5. Patients with a history of malignancy; 6. Patients unwilling to sign the informed consent or unwilling to follow the study protocol for follow-up.
References
Publications (1)
- DERIVEDZhang M, Dong S, Wang L, Liu Z, Zhou H, Liu Q, Chen Y, Tang J, Wang X. Short-term and long-term outcomes of intracorporeal anastomosis in laparoscopic segmental left colectomy for splenic flexure cancer - a multicenter retrospective cohort study of 342 cases. Int J Surg. 2024 Mar 1;110(3):1595-1604. doi: 10.1097/JS9.0000000000000974. PMID 38085798