Clinical trial · Observational
Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The PROSPECT study aims to look at the number of problems or side effects which occur after patients have had a procedure completed to remove fluid or air from the space between the lung and the chest wall. Other information will also be collected to see whether anything else affects which patients have problems after the procedure such as bleeding or infection. This study will also investigate whether it is possible to find out which patients are likely to feel a lot better after the procedure. Not all patients feel significantly better but it is not clear why this is. There are a number of different reasons patients may not feel better, for example if the lung is not able to fully re-expand. The study aims to look at whether it is possible to predict these problems before the procedure using ultrasound. If it is possible to find the answers to some of these questions it might be possible to prevent patients undergoing treatments which are not likely to benefit them. The study will use information already collected as part of clinical care, as well as questionnaires from patients receiving care at a variety of centres. The different features of these centres will also be considered in analysis.
Conditions
Conditions (10)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Complications, Pulmonary | — | UNRESOLVED | — |
| Pleural Diseases | — | UNRESOLVED | — |
| Pleural Effusion | — | UNRESOLVED | — |
| Pleural Effusion, Malignant | — | UNRESOLVED | — |
| Pleural Infection | — | UNRESOLVED | — |
| Pleural Mesothelioma | Pleural Mesothelial Neoplasm | ALIAS | 0.90 |
| Pleural Metastases | — | UNRESOLVED | — |
| Pleural Neoplasms | Pleural Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pneumothorax | — | UNRESOLVED |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pleural interventions | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Undergoing pleural intervention
- description
- Any patient undergoing a pleural procedure (eg thoracocentesis, chest drain, indwelling pleural catheter, pleural biopsies, medical thoracoscopy)
- interventionNames
- Procedure: Pleural interventions
Primary outcomes (1)
- measure
- Complications
- timeFrame
- within 30 days
- description
- Specifically: bleeding, infection, pneumothorax, organ injury, pain, re-expansion pulmonary oedema
Secondary outcomes (1)
- measure
- Patient reported outcome measures of dyspnoea and chest pain
- timeFrame
- within 4 weeks
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Aged \>18 * Undergoing pleural intervention * Able to provide written informed consent Exclusion Criteria: * Aged \<18 * Unable to provide written informed consent
References
Publications (0)
Data not yet available