Clinical trial · Interventional
Prostate Cancer IMAGing IN Early Detection (IMAGINED Trial)
Validation, Calibration, and Translation of Restriction Spectrum Imaging Signal Maps to Enhance MRI Diagnostic Capabilities in Prostate Cancer
NCT05882253CI-TRIAL-00092264IMAGINEDrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The researchers hope to learn if specific types of MRI software and techniques can help improve early prostate cancer detection at time of a MRI-guided prostate biopsy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Restricted Spectrum Imaging-Magnetic Resonance Imaging (RSI-MRI) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- OTHER
- label
- MRI imaging using Siemens MRI
- description
- Participants enrolled will undergo routine Magnetic Resonance Imaging (MRI) to obtain Restricted Spectrum Mapping (RSM). These sequences are acquired at the same time as standard multi-parametric MRI sequences. Second post-processing software then transfers the acquired RSI images from DICOM format and applies a color-coded image that is then overlayed onto the anatomic T2 image.
- interventionNames
- Other: Restricted Spectrum Imaging-Magnetic Resonance Imaging (RSI-MRI)
- type
- OTHER
- label
- MRI imaging using Phillips MRI
- description
- Participants enrolled will undergo routine MRI to obtain RSM. These sequences are acquired at the same time as standard multi-parametric MRI sequences. Second post-processing software then transfers the acquired RSI images from DICOM format and applies a color-coded image that is then overlayed onto the anatomic T2 image.
- interventionNames
- Other: Restricted Spectrum Imaging-Magnetic Resonance Imaging (RSI-MRI)
Eligibility
Eligibility (as posted)
- Sex
- Male
Show eligibility criteria text
Inclusion Criteria: * Selected to undergo an MRI-fusion prostate needle biopsy of the prostate. * Able to provide informed consent Exclusion Criteria: * prior diagnosis of prostate cancer (Grade Group \>1) * metastatic prostate cancer * prior prostate cancer treatment * contraindication to prostate biopsy (e.g., on anticoagulation that cannot be safely discontinued) * inability to undergo MRI (e.g., too large to be accommodated in a scanner or with an implant incompatible with MRI). * Bilateral hip replacement * Unable to provide informed consent.
References
Publications (0)
Data not yet available
No reference posted for this study.