Clinical trial · Observational
Impact of Regional Anesthesia on Chronic Post-operative Pain
Impact of Loco-regional Anesthesia Techniques on Chronic Post-surgery in Breast Oncological Surgery: a Prospective Multicenter Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Approximately 55,000 cases of breast cancer are diagnosed in Italy every year and the first-line therapy for carcinoma in situ, stage I, II and IIIA is surgical removal of the tumour. The incidence of chronic pain after breast cancer surgery is confirmed around 30%. This study aims to evaluate the impact of loco-regional anesthesia techniques in the context of multimodal analgesia in the prevention of chronic pain post-oncological breast surgery
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| analgesia | Drug | — | UNRESOLVED |
| Breast surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients undergoing oncological breast surgery
- description
- * mastectomy + reconstruction * simple quadrantectomy * quadrantectomy + sentinel lymph node biopsy * quadrantectomy + axillary hollowing * bilateral interventions will also be considered
- interventionNames
- Procedure: Breast surgery
- Drug: analgesia
Primary outcomes (1)
- measure
- Incidence of chronic postoperative pain after major breast surgery
- timeFrame
- 6 - 12 months
- description
- Incidence of chronic post-surgical pain after major breast surgery (definition: pain that persists at least 3 months after surgery; pain that was not present before surgery or that has different characteristics from pain before surgery or that has increased intensity than before the operation; the pain is localized in the area of the surgical site or in its radiation; other possible causes of pain are excluded)
Secondary outcomes (5)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria * Age \> 18 * Oncological breast surgery: * simple mastectomy, * mastectomy + sentinel lymph node biopsy, * mastectomy + axillary hollowing, * mastectomy + reconstruction, * simple quadrantectomy, * quadrantectomy + sentinel lymph node biopsy, * quadrantectomy + axillary hollowing, * bilateral interventions will also be considered) Exclusion * Age \< 18
References
Publications (0)
Data not yet available