Clinical trial · Observational
A Multicenter Prospective Cohort Study Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction Failure
NCT05875649CI-TRIAL-00067787CLAGnot yet recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Most of patients with acute myeloid leukemia achieved complete remission (CR) after primary induction chemotherapy, there were 20-30% patients without CR after first-induction. It was uncertain how to treat these patients. It was investigated in our study that these patients were re-induced with CLAG Regimen. The CR ratio, overall survival (OS) and relapsed-free survival (RFS) was statistically analysed in these patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| AML | Acute Myeloid Leukemia | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CLAG | Combination Product | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Group
- description
- Acute myeloid leukemia patients with first-induction failure
- interventionNames
- Combination Product: CLAG
Primary outcomes (1)
- measure
- Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction failure
- timeFrame
- 6 months
- description
- CLAG Regimen improves CR rate in acute myeloid leukemia patients with first-induction failure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 14 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Acute myeloid leukemia patients with first-induction failure Exclusion Criteria: * Acute myeloid leukemia patients with serious infection and organ dysfunction.
References
Publications (0)
Data not yet available
No reference posted for this study.