Clinical trial · Interventional
Navigated Abdominal Lymph Node Dissections
Targeted Abdominal Lymph nodE Dissections Randomized for Surgical NavigaTion (TALENT)
NCT05867095CI-TRIAL-00066540N16LNDcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Image-guided navigation surgery allows for full utilization of pre-operative imaging during surgery, and has the potential of reducing both irradical resections and morbidity. In this study we will randomize patients which will undergo an abdominal lymph node dissection in order to evaluate the actual technical and clinical benefit of navigation
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Image-guide Surgery | — | UNRESOLVED | — |
| Lymph Node Metastasis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional | Procedure | — | UNRESOLVED |
| Surgical navigation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Navigation
- description
- Patients will get the standard of care in the Netherlands with the addition of surgical navigation
- interventionNames
- Procedure: Surgical navigation
- type
- OTHER
- label
- Conventional
- description
- Patients will get the standard of care in the Netherlands
- interventionNames
- Procedure: Conventional
Primary outcomes (1)
- measure
- Number of failed procedures
- timeFrame
- 3 months
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Scheduled for open abdominal surgery in which targeted removal of one or more pathological lymph nodes is part of the surgical plan Exclusion Criteria: * Metal implants in the pelvic area * Contra-indication for contrast enhanced CT scanning
References
Publications (1)
- DERIVEDGroen HC, Wit EMK, Heerink WJ, Kuhlmann KFD, Nijkamp JA, van Veen R, Schoots IG, Balduzzi S, Zijlmans HJMAA, van Leeuwen PJ, van der Poel HG, Ruers TJM. Surgical navigation for targeted retroperitoneal lymph-node removal: a randomised, controlled, phase 3 trial. EClinicalMedicine. 2024 Jul 26;74:102754. doi: 10.1016/j.eclinm.2024.102754. eCollection 2024 Aug. PMID 39737148