Clinical trial · Observational
Clinical Application of 68Ga-FAPI PET Imaging in Detection of Ovarian Cancer Recurrence
NCT05856409CI-TRIAL-00068856unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective study to investigate the potential efficacy of 68Ga-FAPI PET/CT for recurrence detection of epithelial ovarian cancer in comparison with 18F-FDG PET/CT.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| 68Ga-FAPI | — | UNRESOLVED | — |
| Epithelial Ovarian Cancer | Ovarian Carcinoma | ALIAS | 0.90 |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
| Positron Emission Tomography | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 68Ga-FAPI | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Diagnostic Performance
- timeFrame
- 1 year
- description
- Sensitivity and Specificity of 68Ga-FAPI PET/CT for recurrence in comparison with 18F-FDG PET/CT
- measure
- Maximum standardized uptake value（SUVmax）
- timeFrame
- 1 year
- description
- Measurement of the maximum standardized uptake value of the lesion
- measure
- Tumor-to-background ratio (TBR)
- timeFrame
- 1 year
- description
- TBR was calculated according to the formula：TBR=SUVmax of lesion/SUVmax of background
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * adult patients (age\>18 and\<80 years) * patients with clinically suspected recurrent ovarian cancer * patients who underwent paired 18F-FDG and 68Ga-FAPI PET/CT for the most proper treatment strategy within 1 week * patients who did not receive any other treatment 4 weeks before PET imaging Exclusion Criteria: * pregnant patients * patients with poor performance status * patients unwilling to provide written informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.