Clinical trial · Interventional
Efficacy of External Application of Rosemary Oil in Patients With Chemotherapy-Induced Peripheral Neuropathy: a Feasibility Study
Efficacy of External Application of Rosemary Oil in Patients With Chemotherapy-Induced Peripheral Neuropathy - a Monocentre, Single-arm Non-controlled Feasibility Study to Assess the Feasibility of Evaluating Topical Applications in CIPN
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Chemotherapy can cause sensory disorders in the hands and feet called peripheral neuropathy. Typical symptoms are pain, loss of sensation, tingling, numbness, and gait disturbances, which worsen patients' quality of life and increase the risk of falls. Little is known about the effect of rosemary oil (applied to hands and feet) on the symptoms of neuropathy. The present study is a feasibility study to see if it is possible to conduct a clinical trial in patients diagnosed with cancer and receiving chemotherapy who report peripheral neuropathy and apply rosemary oil to their hands and feet.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chemotherapy-induced Peripheral Neuropathy (CIPN) | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Rosemary oil application | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Rosemary oil
- interventionNames
- Other: Rosemary oil application
Primary outcomes (1)
- measure
- Participation rate
- timeFrame
- When participation in the study is offered, before start of chemotherapy and rosemary oil application
- description
- Participation rate in relation to all eligible patients and the reasons for non-participation. Reasons for refusal to participate in the study will be recorded.
Secondary outcomes (2)
- measure
- Rate of fully completed EORTC QLQ-CIPN20 questionnaires
- timeFrame
- Before start of chemotherapy and rosemary oil application (baseline), then weekly for 24 weeks
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Written informed consent * Age 18 years or older * Cancer diagnosis * Assignment to neurotoxic chemotherapy that has not yet started at the time of enrolment * Intact, irritation-free skin on the hands and feet * No history of neuropathic pain Exclusion Criteria: * Neurorelevant comorbidities such as diabetes or alcohol abuse * Use of medication for neuropathy such as gabapentin, pregabalin, venlafaxine or duloxetine * Other relevant treatments for CIPN during the study * Insufficient knowledge of the German language * History of rosemary oil allergy
References
Publications (0)
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