Clinical trial · Interventional
Prehabilitation in Geriatric Patients With Colorectal Neoplasia
Results of a Programme of Intensive Prehabilitation in GEriatric Patients Operated for Colo-Rectal Neoplasia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This an interventional, non-pharmacologic study. Prehabilitation is a multidisciplinary preoperative intervention aimed at preventing or reducing functional decline related to surgery and improving perioperative outcomes. The current study is aimed at standardizing a prehabilitation pathway, evaluating its feasibility within the AUSL Romagna in collaboration with the PRIME Centre and the multiple professions that populate the two institutes in the spirit of confirming the beneficial effect of an integrated prehabilitation programme on surgical outcomes. Patients will follow an intensive prehabilitation course before surgery: * Colon cancer patients will do 4 weeks of prehabilitation before surgery. * Rectal cancer patients will do 12 weeks of prehabilitation after neoadjuvant therapy and before surgery. The prehabilitation course is structured around the following aspects: * Frailty assessment and identification of optimisation fields * Optimisation of modifiable factors (anaemia, polypharmacotherapy, smoking, alcoholism, diabetes) * Assessment by an integrative medicine specialist * Nutritional pre-qualification * Cardiovascular, respiratory, motor prehabilitation * Emotional and psychological prehabilitation
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colo-rectal Cancer | Colon Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prehabilitation course | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Colorectal cancer patients
- description
- Patients with colon or rectal cancer awaiting surgery
- interventionNames
- Other: Prehabilitation course
Primary outcomes (1)
- measure
- Percentage of eligible participants completed the personalized proposed prehabilitation program
- timeFrame
- 4 months
- description
- The primary endpoint of the study will be the feasibility of delivering a prehabilitation program, based on adherence. This study will be deemed as feasible if ≥80% of eligible participants completed the personalized proposed prehabilitation program.
Secondary outcomes (6)
- measure
- Adherence to prescription
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. The participant (or legally acceptable representative if applicable) provides written informed consent for the trial. 2. Male/female participants who are at least 70 years of age on the day of signing informed consent. 3. Patients with confirmed diagnosis of colorectal cancer awaiting major surgery. Exclusion Criteria: 1. Clinical need for emergency intervention. 2. Severe cognitive impairment (MMSE\<20\*) 3. Severe dependency (ADL\<3) 4. Stage IV colorectal neoplasia
References
Publications (0)
Data not yet available