Clinical trial · Interventional
Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs
Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease: Randomized Controlled Trial Among US Adults Who Use LCCs
NCT05849051CI-TRIAL-00084458completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this research is to assess whether little Cigars and cigarillos (LCC) warnings developed by the study team are more effective than the current warnings proposed by FDA for LCC products. A 3-week web-based randomized controlled trial will be conducted in the United States. Participants are adult persons who currently use LCCs.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tobacco Use | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| FDA proposed text-only warnings at 30% size | Behavioral | — | UNRESOLVED |
| Newly developed warnings with images at 30% size | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Newly developed warnings with images
- description
- Participants receive newly developed warnings intervention
- interventionNames
- Behavioral: Newly developed warnings with images at 30% size
- type
- EXPERIMENTAL
- label
- FDA proposed text-only warnings
- description
- Participants receive FDA proposed text only warning intervention
- interventionNames
- Behavioral: FDA proposed text-only warnings at 30% size
- type
- NO_INTERVENTION
- label
- Control group, no intervention
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Members of the recruitment panel (the investigators are partnering with a panel provider for recruitment of all participants) * Agree to provide their honest answers * Current little cigar and/or cigarillo every day or some day users * Over 21 years old * Currently living in US * Feel comfortable taking a survey in English without help * Feel comfortable taking an online survey without help * Have an email address that they check regularly * Have access to the internet at work or home * Able to read and respond to surveys delivered to their email * Able to complete 2 surveys that take approximately 20 minutes * Able to complete a 5 minute survey each day for 20 days * Able to verify they are not a bot using CAPTCHA * Able to answer a simple, random math question Exclusion Criteria: * None
References
Publications (1)
- DERIVEDGoldstein AO, Jarman KL, Ranney LM, Cornacchione Ross J, Kowitt SD, Enyioha C, Clark SA, Sheeran P, Thrasher JF, Jenson D, Vielot NA. Little Cigar and Cigarillo Graphic Health Warnings and Quitting Behaviors: A Randomized Clinical Trial. JAMA Netw Open. 2025 Aug 1;8(8):e2526799. doi: 10.1001/jamanetworkopen.2025.26799. PMID 40815515