Clinical trial · Interventional
InveStigAting Bladder fiELd-cycLing imAging
InveStigAting Bladder fiELd-cycLing imAging (ISABELLA)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): No participants identified. Funding ended
Summary
Brief summary (as posted)
The goal of this pilot study is explore the parameters that can be obtained in bladder tumours by Field-Cycling Imaging (FCI) in patients with both muscle-invasive and non-muscle invasive tumours. The main question it aims to answer is if FCI can give more diagnostic information than conventional tests. Participants will have one FCI scan and the results will be correlated with the results of CT urogram or CT scan.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Field-Cycling Imaging (FCI) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Bladder tumours
- description
- Participants with muscle-invasive and non-muscle invasive bladder tumours of at least 3 cm in diameter will undergo one FCI scan.
- interventionNames
- Device: Field-Cycling Imaging (FCI)
Primary outcomes (1)
- measure
- Identification of bladder tumours by Field-Cycling Imaging (FCI) scan
- timeFrame
- At baseline
- description
- Validation of FCI T1 dispersion profiles as a non-invasive technology able to detect bladder tumours.
Secondary outcomes (1)
- measure
- Differentiation of bladder tumours assessed by Field-Cycling Imaging (FCI) T1 dispersion profiles
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients attending for flexible cystoscopy found to have a tumour of at least 3 cm in diameter (muscle-invasive or non-muscle invasive) * Participants must be aged 18 and above * Participants who meet the safety criteria for undergoing an MRI scan * Participants who are able to fit inside the scanner * Participants must be able to give fully informed consent * Participants must be mobile enough to be positioned onto the FCI scanner couch Exclusion Criteria: * Patients with total hip replacement * MRI-incompatible conditions, as detected in the MRI safety screening sheet * Participants under 18 years old * Participants who are unable to communicate in English * Participants who are unable to give fully informed consent * Women who are pregnant * Restrictions to mobility that would prevent the correct positioning in the scanner * Participants who suffer from claustrophobia
References
Publications (0)
Data not yet available