Clinical trial · Interventional
Patients With Stage III-IVa Nasopharyngeal Carcinoma With or Without a Mobile Medical Platform Full-course Nutritional Intervention
A Randomized, Controlled, Phase II Clinical Study on the Improvement of Malnutrition in Patients With Stage III-IVa Nasopharyngeal Carcinoma With or Without the Use of Mobile Medical Platform Full-course Nutritional Intervention
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To study the difference in the proportion of patients with nasopharyngeal carcinoma who lost more than 10% of their body weight within 1 month after radiotherapy and chemotherapy using the mobile platform for whole-process individualized nutritional rehabilitation management compared with conventional nutritional rehabilitation management.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nasopharyngeal Carcinoma | Nasopharyngeal Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| mobile platform or not mobile platform | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Mobile Platform Intervention Group
- description
- The mobile platform is used to evaluate the nutrition of patients 2 weeks after the first course of induction chemotherapy, before radiotherapy, during radiotherapy, after radiotherapy, and 1 month after radiotherapy. The doctor pushes individualized nutrition education, oral advice, medication advice, etc. .
- interventionNames
- Device: mobile platform or not mobile platform
- type
- ACTIVE_COMPARATOR
- label
- Non-mobile Platform Intervention Group
- description
- Nutritional assessment of patients was performed at 2 weeks after 1 course of induction chemotherapy, before radiotherapy, during radiotherapy, at the end of radiotherapy, and at 1 month after the end of radiotherapy.
- interventionNames
- Device: mobile platform or not mobile platform
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * 1.Voluntarily participate and sign the informed consent in writing. * 2.Stage III-IVa (AJCC 8th edition staging) . * 3.Received induction chemotherapy + concurrent chemoradiotherapy . * 4.18-70 years old. * 5.Pathologically diagnosed with non-keratinizing nasopharyngeal carcinoma (differentiated or undifferentiated, that is, WHO type II or III). * 6.No previous anti-tumor therapy . * 7.ECOG score 0-1. * 8.Ensure contraception during the study period. * 9.Hemoglobin (HGB) ≥90 g/L, white blood cell (WBC) ≥4×109/L, platelet (PLT) ≥100×109/L. * 10\. Liver function: ALT, AST \< 2.5 times the upper limit of normal (ULN), total bilirubin \< 2.0 × ULN. * 11\. Renal function: serum creatinine \<1.5×ULN. * 12.Able and willing to use a mobile phone or tablet to fill in the electronic scale. Exclusion Criteria: * 1.Received antitumor therapy in the past. * 2\. The pathology was keratinizing squamous cell carcinoma (WHO type I). * 3.Pregnant women who are in the reproductive period and have not taken effective contraceptive measures. * 4\. Has suffered from other malignant tumors (except for cured basal cell carcinoma or carcinoma in situ of the cervix). * 5.Patients with significantly low heart, liver, lung, kidney and bone marrow functions. * 6.Serious, uncontrolled medical diseases and infections. * 7.Concurrent use of other experimental drugs or other clinical trials. * 8\. Refused or unable to sign the informed consent to participate in the trial. * 9.Those who have other contraindications to treatment. * 10.Persons with personality or mental disorders, no capacity for civil conduct or limited capacity for civil conduct.
References
Publications (0)
Data not yet available