Clinical trial · Observational
Lung Tumor Protein Synthesis Rates in Lung Cancer Patients
Characterizing Tissue Protein Synthesis Rates of Non-small Cell Lung Carcinomas in Lung Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The current study will recruit lung cancer patients to measure tissue protein synthesis rates of non-small cell lung carcinomas and healthy lung tissue. The protein synthesis rates of healthy lung tissue will be compared to lung tumor tissue to establish the remodeling characteristics of healthy versus cancerous lung tissues. We will also examine whether tissue protein synthesis rates of non-small cell lung carcinomas are associated with various tumor- (i.e., size, subclassification) and patient-derived (i.e., inflammation, lung function, smoking status, and smoking history) parameters.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| There are no interventions in the present study | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Lung cancer patient
- description
- Lung cancer patients diagnosed a non-small cell lung carcinoma requiring resection surgery.
- interventionNames
- Other: There are no interventions in the present study
Primary outcomes (3)
- measure
- Lung tumor fractional synthetic rate
- timeFrame
- 5 days prior to surgery
- description
- units: % per day
- measure
- Lung tissue fractional synthetic rate
- timeFrame
- 5 days prior to surgery
- description
- units: % per day
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: 1. Aged 18-65 years 2. Compos mentis 3. Diagnosed with lung cancer, with treatment requiring a thoracotomy or VATS lobectomy Exclusion Criteria: 1. Neoadjuvant chemo- or radiotherapy in the past four weeks 2. Use of systemic steroids in the past four week 3. Insulin-dependent diabetes mellitus 4. Pregnancy
References
Publications (0)
Data not yet available