Clinical trial · Observational
Multi-Cancer Early Detection (MCED) of Firefighters
NCT05780957CI-TRIAL-00097002recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is an an observational prospective cohort research study to explore the performance of new blood and urine tests for the early detection of cancer among firefighters.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MCED | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Firefighters who receive multi-cancer early detection (MCED) test
- interventionNames
- Other: MCED
Primary outcomes (2)
- measure
- Sensitivity, specificity, positive and negative predictive performance values (PPV and NPV) to detect cancer using Elypta's MCED test, as measured in plasma, in urine, and in plasma and urine combined
- timeFrame
- Up to 7 years
- measure
- Sensitivity, specificity, positive and negative predictive performance values to detect cancer using Proteotype's MCED test, as measured in plasma.
- timeFrame
- Up to 2030
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years of age or older * Currently employed as a firefighter, full-time or part-time * Taking part in Vincere's First Responder Cancer Screening Program * Able to donate blood and urine sample * Able to provide informed consent to participate in the study Exclusion Criteria: * Deemed medically unfit for sample donation * Personal history of cancer in the last 5 years (with the exception of non-melanoma skin cancer)
References
Publications (0)
Data not yet available
No reference posted for this study.