Clinical trial · Interventional
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
NCT05773144CI-TRIAL-00100265ACTIONrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Neoplasms | Colon Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic exercise | Behavioral | — | UNRESOLVED |
| Progressive stretching | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- type
- SHAM_COMPARATOR
- label
- Attention control
- description
- Static stretching
- interventionNames
- Behavioral: Progressive stretching
- type
- EXPERIMENTAL
- label
- 75 min/wk aerobic exercise
- description
- Aerobic exercise at a dose of 75 minutes per week
- interventionNames
- Behavioral: Aerobic exercise
- type
- EXPERIMENTAL
- label
- 150 min/wk aerobic exercise
- description
- Aerobic exercise at a dose of 150 minutes per week
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥18 years * Histologically confirmed stage II or III colon cancer * Completed surgical resection with curative intent * Plan to initiate chemotherapy * Engage in \<60 minutes per week of moderate- to vigorous-intensity structured aerobic exercise * No planned major surgery during the study period * Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire * Can walk 400 meters * Can read and speak English * Ability to provide written informed consent * Provide written approval by qualified healthcare professional * Willing to be randomized Exclusion Criteria: * Evidence of metastatic colon cancer * Concurrently actively treated other (non-colon) cancer * Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks * Currently participating in another study with competing outcomes * Any other condition that, in the opinion of the investigator, would preclude participation or successful compliance with the protocol * Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol
References
Publications (0)
Data not yet available
No reference posted for this study.