Clinical trial · Interventional
Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing
NCT05759143CI-TRIAL-00123987active not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research is being done to develop the electronic platform Nest for young adults (ages 18-39) who have had prior cancer genetic testing. The platform will give patients and their clinicians access to continuously updated information about both pathogenic variants and variants of uncertain significance (VUS). The name of the intervention used in this research study is: Nest portal (electronic platform for patients and clinicians)
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Genetic Predisposition | — | UNRESOLVED | — |
| Genetic Predisposition to Disease | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nest Platform | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Nest Refinement Phase
- description
- 20 participants and clinicians will complete study procedures as outlined: * Nest portal orientation and access. * Semi-structured, 30-minute interviews. Solicited feedback on content and processes will refine the intervention for a pilot phase.
- interventionNames
- Behavioral: Nest Platform
- type
- EXPERIMENTAL
- label
- Nest Pilot Phase
- description
- 10 Participants and 10 clinicians will complete study procedures as outlined: * Baseline survey (participant). * Standard clinic visit. * Nest portal orientation and access (participant and clinician). * Post-visit survey (participant and clinician). * Brief, 30-minute, semi-structured interview (participant and clinician).
- interventionNames
- Behavioral: Nest Platform
Primary outcomes (5)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 39 Years
Show eligibility criteria text
Inclusion Criteria AIM 1: * YA Patients: * Ages 18-39 years, inclusive. * Has had previous cancer genetic testing, with a finding of a pathogenic variant or VUS; patient has previously received results from the clinical team. * English-speaking and -reading. * Receiving care at DFCI. * Not undergoing active cancer therapy at the time of approach. * Clinicians: * Cancer risk physicians (oncologists, gastroenterologists, geneticists), oncologists, nurse practitioners, physician assistants, or genetic counselors. * English-speaking and -reading. * Cares for YAs aged 18-39 with cancer risk syndromes. Inclusion Criteria AIM 2: * YA Patients: * Ages 18-39 years, inclusive. * Has had previous cancer genetic testing, with a finding of a pathogenic variant or VUS; patient has previously received results from the clinical team. * English-speaking and -reading. * Receiving care at Dana-Farber Cancer Institute. * Did not participate in a stakeholder interview (Aim 1). * Not undergoing active cancer therapy at the time of approach. * Clinicians: * Oncologists, nurse practitioners, cancer risk physicians, or genetic counselors. * English-speaking and -reading. * Caring for a participating YA.
References
Publications (0)
Data not yet available
No reference posted for this study.