Clinical trial · Interventional
Effect Of High Power Laser On Radiotherapy Induced Trismus.
Effect Of High Power Laser Therapy On Radiotherapy Induced Trismus In Head And Neck Cancer Patients
NCT05757024CI-TRIAL-00064510unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
this study Randomized controlled study will be conducted to study (the effect of high power laser therapy on radiotherapy induced trismus in head and neck cancer patients). the study group will receive high power laser therapy in combination with conventional tempromandibular joint exercises. the control group will receive conventional tempromandibular joint exercises.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Trismus | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| high power laser therapy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- experimental group
- description
- study group receive high power laser therapy in combination with conventional tempromandibular joint exercises.
- interventionNames
- Device: high power laser therapy
- type
- ACTIVE_COMPARATOR
- label
- control group
- description
- control group receive traditional tempromadibular joint exercises.
- interventionNames
- Device: high power laser therapy
Primary outcomes (2)
- measure
- pain level
- timeFrame
- one month (4 weeks)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * head and neck cancer patients who complain of decreased mouth opening and received or receiving radiotherapy. * patients who complain from pain and inflammation in the tempromandibular joint due to radiotherapy. * radiotherapy should be above 40 GY. * patient ages between 20 to 65 years old. Exclusion Criteria: * patients with poor general health. * patients with difficulties in filling questionnaire. * patients who are complaining of other tempomandibular problems other than trismus such as (disc discplacement and trumatic mandibular fractures.
References
Publications (2)
- RESULTZecha JA, Raber-Durlacher JE, Nair RG, Epstein JB, Elad S, Hamblin MR, Barasch A, Migliorati CA, Milstein DM, Genot MT, Lansaat L, van der Brink R, Arnabat-Dominguez J, van der Molen L, Jacobi I, van Diessen J, de Lange J, Smeele LE, Schubert MM, Bensadoun RJ. Low-level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 2: proposed applications and treatment protocols. Support Care Cancer. 2016 Jun;24(6):2793-805. doi: 10.1007/s00520-016-3153-y. Epub 2016 Mar 17. PMID 26984249
- RESULTBorges, Marcela Maria Fontes, et al.