Clinical trial · Observational
Cognitive Processing Slowness as a Marker of Cognitive Impairment in Non-central Nervous System Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cancer is a frequent disease considering that one person out of three will be confronted with it in their lifetime. Cancer patients often express complaints related to cognitive impairment as an outcome of their oncological treatment. These cognitive disorders have a significant impact on the patient's and their carer's quality of life. Therefore, it appears necessary to have a reliable, quick and simple tool in order to detect cognitive impairment. The rationale of this study relies on 3 main points : * The cognitive complaint frequently reported by cancer patients * The difficulty in reliably demonstrating the cause of this complaint through conventional neuropsychological tests * The interest of cognitive processing speed as an indicator of cognitive dysfunction The primary objective of the study is to evaluate a potential variation of cognitive processing speed at the Saint-Louis Lille Battery (SSLIB) between the beginning and during (4 months after the beginning) the oncological treatment of adults with breast cancer or colon cancer.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Cognitive Impairment | — | UNRESOLVED | — |
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Saint-Louis Lille Battery (SSLIB) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Saint-Louis Lille Battery (SSLIB)
- description
- Saint-Louis Lille Battery (SSLIB) is composed of three tests studying the speed of cognitive processing and proposed to the subjects on a tactile tablet. These three tasks are: (a) Reaction time tasks specifically developed for this study b) A digital adaptation of the WAIS-IV code subtest c) A digital version of the Trail Making Test (A and B)
- interventionNames
- Other: Saint-Louis Lille Battery (SSLIB)
Primary outcomes (1)
- measure
- Proportion of patients for which there is a variation of reaction time between the beginning and during the oncological treatment at M4
- timeFrame
- At 4 months
- description
- The variation will be defined as follows : * Mild if the reaction times vary for only one of the Saint-Louis Lille Battery (SLLIB) tests * Moderate if the variation appears on two of the SLLIB tests * Severe if the variation appears on three of the SLLIB tests
Secondary outcomes (11)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Beginning an oncological treatment for breast or colon cancer * Patients of age ≥ 20 and ≤ 70 years old * Cancer diagnosis announcement delivered since less than 3 weeks (+/- a week) * Patient affiliated to French social security Exclusion Criteria: * Patient's opposition to the study * Notion of an abnormal cerebral scan or MRI * Drug use (alcohol, narcotics…) * Chronic (≥ 15 days) treatment with corticosteroids \> 1mg/kg/j (prednisone or equivalent) * Ocular pathology or cognitive disorder impairing comprehension and reading abilities * Patients under curatorship, guardianship or under the protection of justice
References
Publications (0)
Data not yet available