Clinical trial · Observational
Prediction of Myocardial Injury After Laparoscopic Pheochromocytoma/ParaGangLioma Resection
Risk Identification and Prediction of Myocardial Injury After Laparoscopic Pheochromocytoma/Paraganglioma Resection:A Ambispective Cohort Study.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational study was conducted in patients undergoing elective laparoscopic pheochromocytoma/paraganglioma(PPGL) resection. It mainly answers the following two main questions: 1. What are the risk factors for myocardial injury after laparoscopic PPGL resection？ 2. How to establish the myocardial injury prediction model of laparoscopic PPGL resection? Participants were not required to perform additional research work other than the usual postoperative follow-up within 30 days after surgery. No control group was set in this study, and no additional clinical intervention was performed.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| PGL | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Myocardial injury after laparoscopic PPGL resection
- timeFrame
- 30days after surgery
- description
- Myocardial injury was defined as an elevated troponin I level exceeding the 99th percentile upper reference limit due to cardiac ischemic causes.
Secondary outcomes (5)
- measure
- Acute myocardial infarction
- timeFrame
- 30days after surgery
- description
- An increase in troponin exceeding 99% of the reference limit is associated with at least one of the following: 1. Symptoms of myocardial ischemia; 2. New ECG ischemic changes (ST elevation or depression or abnormal Q wave; 3. Imaging findings of abnormal new ventricular wall movement or loss of viable myocardia consistent with ischemic etiology; 4. Coronary thrombosis was confirmed by coronary intervention (angiography) or autopsy.
- measure
- Nonfatal cardiac arrest
- timeFrame
- 30days after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Scheduled for Laparoscopic PPGL resection Exclusion Criteria: 1. Open or laparoscopic conversion to open PPGL resection was excluded 2. Cardiac paraganglioma was excluded 3. History of congenital heart disease or cardiac surgery was excluded 4. Patients with preoperative troponin/hypersensitive troponin elevation were excluded 5. Carotid body tumor and accessory ganglioma of jugular tympanum without endocrine function were excluded
References
Publications (1)
- DERIVEDLan L, Ma Y, Zhao Y, Li Y, Zhang Y, Shen L, Zhang Y, Huang Y. Prediction of postoperative myocardial injury in patients undergoing laparoscopic pheochromocytoma/paraganglioma resection: protocol for an ambispective cohort study. BMJ Open. 2025 Feb 7;15(2):e091975. doi: 10.1136/bmjopen-2024-091975. PMID 39920072