Clinical trial · Observational
EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Breast CA
Prospective Study of an EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to learn how a group resistance training plan can improve body mobility and strength in female breast cancer patients who have completed their breast cancer treatment. The main questions it aims to answer are: * Is resistance training feasible following breast cancer treatment * Can it improve the body's mobility and strength lost as a result of the breast cancer treatment * can it improve the body's composition (for example muscle mass) * can resistance training increase one's activity level and help prevent weight gain, perhaps, lowering the risk of cancer recurrence. Participants will attend a group resistance training exercise group program, 3-4 times per week, under close supervision with monitoring a participant's ability to safely and effectively complete the program. The exercises include: lunges, squats and dead lifts.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Female | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Observation of Exercise Program Adherence | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Standard High-load resistance training
- description
- Standard exercise regimen utilizes a mixture of compound and isolated movements, focusing on compound exercises. The regimen is a typical standard of care resistance training program and sports performance and strength and conditioning facilities. The observed classes will take place three times per week. Warm-up exercises focused on mobility, flexibility and core activation will be performed to reduce the risk of injury. Each individual exercise workout will generally progress from most intense, CKC, compound, and athletic movements to least intense throughout the workout to maximize safety. Additionally, each workout will provide full body resistance training to focus on functional exercises, intensity, and efficiency. Each workout will take approximately 45 minutes. The total exercise regimen will last 3 months.
- interventionNames
- Other: Observation of Exercise Program Adherence
Primary outcomes (11)
- measure
- Session Attendance
- timeFrame
- Baseline and Three (3) months
- description
- Calculated as the percentage of participants completing at least 75% of the planned exercise sessions. Dropout rate, defined as individuals who quit the workout regimen altogether, is expected to be less 20%.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 89 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age 20-89 years 2. Women with a biopsy proven diagnosis of ductal carcinoma in situ or invasive carcinoma of the breast 3. Women must have undergone breast conservation therapy with no neoadjuvant or adjuvant chemotherapy (adjuvant endocrine therapy is permitted) 4. Participants must have abstained from smoking for at least 12 months 5. Women of child-bearing potential must have had a pregnancy test prior to initiation of radiation therapy (standard protocol for radiation therapy); verbally confirm lack of pregnancy prior to enrollment; and, consent to use adequate contraception during the course of the study. 6. Participants must be determined capable of engaging in resistance training. 7. Participants must have a schedule amenable to three prescheduled workout sessions per week, scheduled during the day. 8. Participants must complete a Functional Mobility Screen (FMS) and be determined safe to engage in the workout regimen by the study exercise personnel. 9. Participants must be determined capable of engaging in group resistance training sessions by exercise personnel and/or study PI 10. Participants must be able to get down and up from the ground and squat their body weight. Exclusion Criteria: 1. Any treatment with chemotherapy for breast cancer 2. Inability to get and down off the ground or squat body weight 3. Inability to safely engage in group sessions 4. Severe arthritic, joint, cardiovascular, or musculoskeletal condition
References
Publications (1)
- DERIVEDCarpenter DJ, Peluso C, Hilton C, Velasquez F, Annichine A, Matsko K, Rosenberg J, Diaz AK, Hyde P, Beriwal S, Champ CE. EXERT-BC: A pilot study of an exercise regimen designed to improve functional mobility, body composition, and strength after the treatment for breast cancer. Cancer Med. 2024 Mar;13(5):e7001. doi: 10.1002/cam4.7001. PMID 38491821