Clinical trial · Observational
Clinico-immunological Characterization and Immune Tolerance Breakdown in HU-autoimmunity
NCT05745792CI-TRIAL-00064281CarTo-HuunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Phenotypic characterization of patients with Hu-Abs, including the different neurological presentation and the presence or not of an underlying cancer. Analysis and clinical correlation of the diagnostic techniques for Hu-Abs detection (immunofluorescence, immunodot/Western blot, and CBA) in serum and/or CSF. Genomic and transcriptomic features of tumors (histological and immune infiltrate characteristics, transcriptomic profile, mutational status).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Immune Tolerance | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Description of clinical, immunological and tumor features of patients harboring Hu Abs | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with Hu Abs
- description
- Patients harboring Hu Abs and a neurological syndrome
- interventionNames
- Other: Description of clinical, immunological and tumor features of patients harboring Hu Abs
Primary outcomes (1)
- measure
- Modified Rankin Scale (mRs)
- timeFrame
- At 1 year
- description
- Application of modified rankin scale
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
* Inclusion Criteria \* : * Patient with neurological disorder * Patient with Hu antibody in sera or CSF * Exclusion Criteria \* : * Patient with no data * Patient without neurological disorder * Patient without Hu antibody in sera/CSF
References
Publications (0)
Data not yet available
No reference posted for this study.