Clinical trial · Observational
Effect of Sleep Disorder on the Development of Lung Tumors
Effect of Sleep Disorder on the Development of Lung Tumors, a Perspective, Single-centered Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to observe the lung tumor development in lung tumor patients with long-term sleep disorder. The main questions it aims to answer are: * will long-term sleep disorder promote the malignancy of lung tumor * if so, how exactly will the microenvironment of lung tumor change Participants will receive PSQI scale and MRI functional brain imaging before surgery, blood and tumor tissue will be collected during the surgery. Researchers will set non-sleep disorder group as control group to see if lung tumor microenvironment change when long-term sleep disorder exists in lung tumor patiens.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Sleep Disorder, Lung Tumor | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- CRD
- description
- patients whose PSQI score\>5
- label
- non-CRD
- description
- patients whose PSQI score ≦ 5
Primary outcomes (1)
- measure
- tumor microenvironment in sleep-disordered lung cancer patients
- timeFrame
- 3 months after surgery
- description
- we use single cell sequencing to analyze microenvironment alterations of tumor tissues in enrolled patients.
Secondary outcomes (2)
- measure
- peripheral blood levels of neurotransmitters in sleep-disordered lung cancer patients
- timeFrame
- 3 months after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * 18-75 years old * elective sublobectomy for primary lung tumor * ASA grade I-II * Informed consent of the patient or family Exclusion Criteria: * Combination of serious heart, liver, kidney, central nervous system, blood system, immune system diseases or serious mental illness * Combination of other cancers * untreated active lung infection * patients with preoperative neoadjuvant radiotherapy
References
Publications (0)
Data not yet available