Clinical trial · Interventional
A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions
Multicenter, Open-label, Prospective Randomized Controlled Trial of Radial Endobronchial Ultrasonography and Virtual Bronchoscopy Navigation for the Peripheral Pulmonary Lesions
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Peripheral pulmonary lesions are of growing importance in respiratory field. Early detection of lung cancer, tuberculosis and other diseases often needs a bronchoscopic investigation with different types of navigation. Current randomized clinical study is intended to compare three different modalities of navigation in bronchial tree - virtual bronchoscopy (VBN), radial endobronchial ultrasound (EBUS) and combination of both techniques.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Pneumonia | — | UNRESOLVED | — |
| Tuberculosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| radial EBUS | Diagnostic Test | — | UNRESOLVED |
| Virtual bronchoscopy navigation | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- VBN
- description
- Virtual bronchoscopy
- interventionNames
- Diagnostic Test: Virtual bronchoscopy navigation
- type
- EXPERIMENTAL
- label
- VBN+rEBUS
- description
- Combination of VBN and radial EBUS
- interventionNames
- Diagnostic Test: Virtual bronchoscopy navigation
- Diagnostic Test: radial EBUS
- type
- ACTIVE_COMPARATOR
- label
- rEBUS
- description
- Radial EBUS as a gold standard
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients with newly diagnosed unverified solitary or multiple (up to 3) peripheral pulmonary lesions (PPLs) 2. PPL size 5 - 40 mm 3. Actual chest CT scan (\<31 days prior to navigation bronchoscopy), collimation 1 mm, pulmonary window, DICOM format 4. Age \> 18 years 5. Signed Informed consent form 6. Willing and ability to undergone a navigational bronchoscopy Exclusion Criteria: 1. Unability to undergone navigation bronchoscopy for any reason 2. Any malignant disease during last 36 months 3. Known central endobronchial lesion of any cause 4. HIV-infection
References
Publications (0)
Data not yet available