Clinical trial · Observational
ORganoid GeneratioN Study for Cancer
NCT05734963CI-TRIAL-00079654ORIGINSrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
ORIGINS - a multi-site sample collection study to establish patient-derived pre-clinical models for cancers
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| DNA sequencing, RNA gene expression analysis, molecular profiling | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Group 1
- description
- Patients with histologically confirmed cancer Tissue, blood and saliva samples collected before and after surgery and before and after any adjuvant therapy. Molecular profiling, DNA sequencing, gene expression analysis
- interventionNames
- Genetic: DNA sequencing, RNA gene expression analysis, molecular profiling
Primary outcomes (1)
- measure
- Establish patient-derived organoid (PDO) model for cancers
- timeFrame
- Time Frame: Through study completion, expected duration of 9 years
- description
- Establish patient-derived organoid (PDO) model for cancers
Secondary outcomes (5)
- measure
- To collection contemporaneous biological samples from patients with cancer before and after surgery/biopsy, and again after any adjuvant therapy
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 years or older * Patients with histologically proven or suspected cancer undergoing an interventional procedure, such as surgery or biopsy * Ability to give informed consent for biological sample collection Exclusion Criteria: * Unable to undergo sample collection * Pregnancy
References
Publications (0)
Data not yet available
No reference posted for this study.