Clinical trial · Interventional
Clinical Pilot Study for Personalized Risk-based Breast Cancer Screening
NCT05731453CI-TRIAL-00077424active not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study aims to evaluate the impact of implementing population-based genetics testing strategy for breast cancer precision prevention using the polygenic risk score and monogenic pathogenic variant (MPV) testing in the Norwegian healthcare setting.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Polygenetic risk score | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Polygenetic risk score
- description
- Assessment of polygenetic risk score for breast cancer
- interventionNames
- Genetic: Polygenetic risk score
Primary outcomes (1)
- measure
- Assessment of breast cancer risk by polygenetic risk score in the study population
- timeFrame
- 10 years
- description
- Polygenetic breast cancer risk score (PRS) as a numeric value with 10 percentile, as absolute 10-year breast cancer risk, and as relative risk compared with average women at the same age
Secondary outcomes (3)
- measure
- Compliance to individual recommedations for breast cancer screening
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 40 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * Women referred for clinical mammography in the Vestre Viken Breast Centre * Breast density BI-RADS a or d * 40-50 y.o. Exclusion Criteria: * Prior history of breast cancer or premalignant breast disease * Prior genetic counselling/testing
References
Publications (0)
Data not yet available
No reference posted for this study.