Clinical trial · Observational
Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Endoscopic resection of superficial colorectal neoplasms decrease risk of colorectal cancer. En bloc resection is necessary for large superficial lesions with risk of superficial submucosal cancer and is advised if feasible for all lesions. Endoscopic submucosal dissection (ESD) allows en bloc resection of large superficial colorectal neoplasms, increasing curative resection rate and decreasing local recurrence risk. However, the risk of perprocedural or delayed perforation is higher compared to wild field piece meal endoscopic mucosal resection. Endoscoping clipping and closing methods mostly allow conservative treatment, but some case still necessitate surgery. The aim of our study is to describe and ananalyse outcomes after perprocedural or delayed perforation in all patients undergoing ESD and analyse the need for surgical intervention.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Perforation Colon | — | UNRESOLVED | — |
| Perforation of Rectum | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic submucosal dissection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Perforation
- description
- all patients with immediate or delayed perforation identified from the FECCO (NCT04592003)
- interventionNames
- Procedure: Endoscopic submucosal dissection
Primary outcomes (1)
- measure
- Surgery
- timeFrame
- 30 days
- description
- Rate of surgery following perforation after ESD
Secondary outcomes (6)
- measure
- Hospital stay
- timeFrame
- 60 days
- description
- length of hospital stay (days)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients from the FECCO (NCT04592003) cohort experiencing perprocedural or delayed perforation * age over 18 years old Exclusion Criteria: * patients refusing exploitations of health datas * patient treated with endoscopic mucosal resection
References
Publications (0)
Data not yet available