Clinical trial · Interventional
Pectoral Nerve Block During Mastectomy
The Effect of Pectoral Nerve Block as a Part of Enhanced Recovery After Mastectomy
NCT05699902CI-TRIAL-00063465PNBunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Impact of pectoral nerve block on postoperative pain and quality of recovery in patients undergoing breast cancer surgery: A prospective study
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Female | — | UNRESOLVED | — |
| Pain, Postoperative | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PECs block during mastectomy | Procedure | — | UNRESOLVED |
| Sham block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- PECs block group
- description
- Female undergone mastectomy and received pectoral nerve block
- interventionNames
- Procedure: PECs block during mastectomy
- type
- SHAM_COMPARATOR
- label
- Non PECs block group
- description
- Female undergone mastectomy and not received pectoral nerve block but have received conventional analgesic methods
- interventionNames
- Procedure: Sham block
Primary outcomes (1)
- measure
- Post operative pain
- timeFrame
- 1year
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1- all female planed for elective breast surgery Exclusion Criteria: 1. Planned for bilateral axillary or bilateral reconstruction surgery. * Previous surgery on the surgical breast and/or axilla with the exception of partial mastectomy or sentinel lymph node biopsy Pre-existing pain in the axilla affecting the ability to use extremity for activities of daily living or requiring medication for treatment. 2. Current or past medical history of liver disease or cirrhosis with an elevated INR \>1.4 or currently elevated transaminase levels. 3. known contraindications to peripheral nerve block placement. 4. Pregnant or breastfeeding. 5. History of allergic reactions attributed to compounds of similar chemical or biologic composition 6. Planned additional surgery to the surgical breast or axilla in the next year (exception would be minor surgery to breast but not axilla such as simple tissue expander replacement or lumpectomy).
References
Publications (3)
- BACKGROUNDUeshima H, Otake H, Hara E, Blanco R. How to Use Pectoral Nerve Blocks Effectively-An Evidence-Based Update. Asian J Anesthesiol. 2019 Jun 1;57(2):28-36. doi: 10.6859/aja.201906_57(2).0002. PMID 31382323
- BACKGROUNDAarab Y, Ramin S, Odonnat T, Garnier O, Boissin A, Molinari N, Marin G, Perrigault PF, Cuvillon P, Chanques G. Pectoral Nerve Blocks for Breast Augmentation Surgery: A Randomized, Double-blind, Dual-centered Controlled Trial. Anesthesiology. 2021 Sep 1;135(3):442-453. doi: 10.1097/ALN.0000000000003855. PMID 34195767
- BACKGROUNDDaniel Pereira D, Bleeker H, Malic C, Barrowman N, Shadrina A. Pectoral nerve block and acute pain management after breast reduction surgery in adolescent patients. Can J Anaesth. 2021 Oct;68(10):1574-1575. doi: 10.1007/s12630-021-02037-8. Epub 2021 Jun 3. No abstract available. PMID 34081262