Clinical trial · Interventional
Outpatient Ultrasound for the Diagnostic Work-up of Oropharynx Cancer
Surgeon-performed Outpatient Transoral and Transcervical Ultrasound for the Diagnostic Work-up of Oropharynx Cancer: a Feasibility Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of the study was to examine the detection rate and tumor size evaluation in patients with suspected oropharynx cancer using a new technique with transoral ultrasound of the oropharynx. The new technique was compared to Magnetic Resonance Imaging (MRI). The study investigators included patients referred to a tertiary head \& neck cancer center in Copenhagen, Denmark, with suspicion of oropharynx cancer. Patients supplied written informed consent and were included and ultrasound scanned with local anesthesia in the outpatient clinic. Blinded assessment of MRI's was performed for tumor detection and compared to ultrasound with the reference standard being histopathology biopsy results.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Base of Tongue Carcinoma | Posterior Tongue Carcinoma | ALIAS | 0.90 |
| Base of Tongue Tumor | Posterior Tongue Neoplasm | ALIAS | 0.90 |
| Oropharynx Cancer | Malignant Oropharyngeal Neoplasm | ALIAS | 0.90 |
| Oropharynx Neoplasm | — | UNRESOLVED | — |
| Tonsil Cancer | — | UNRESOLVED | — |
| Tonsil Hypertrophy | — | UNRESOLVED | — |
| Tonsil Lymphoma | Tonsillar Lymphoma | ALIAS | 0.90 |
| Tonsil Neoplasm | Tonsillar Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Transcervical ultrasound | Diagnostic Test | — | UNRESOLVED |
| Transoral ultrasound | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Oropharynx Ultrasound
- description
- Transoral and transcervical ultrasound of the oropharynx, including the tonsils and tongue base.
- interventionNames
- Diagnostic Test: Transoral ultrasound
- Diagnostic Test: Transcervical ultrasound
Primary outcomes (1)
- measure
- Proportion of patients with oropharynx cancer detected by ultrasound compared to MRI
- timeFrame
- Within two weeks.
- description
- Patients with cancer (histopathology verified) correctly detected by a positive ultrasound or MRI test result.
Secondary outcomes (2)
- measure
- Greatest tumor diameter compared between ultrasound and MRI.
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria (any of the following): * Visible and/or palpable tumor or asymmetry of the tonsils, tongue base or oropharynx. * Subjective symptoms of oropharynx cancer including dysphagia, odynophagia and/or referred otalgia. Exclusion Criteria: * Unable to understand Danish or English. * Unable to provide written informed consent. * Age younger than 18 years.
References
Publications (0)
Data not yet available