Clinical trial · Observational
International Rare Brain Tumor Registry
NCT05697874CI-TRIAL-00120967IRBTRrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of the International Rare Brain Tumor Registry (IRBTR) is to better understand rare brain tumors through the collection of biospecimens and matched clinical data of children, adolescents, and young adult patients diagnosed with rare brain tumors.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Astroblastoma | Astroblastoma, MN1-Altered | ALIAS | 0.90 |
| BCOR ITD Sarcoma | BCOR ITD Sarcoma | ONTOLOGY_EXACT | 0.98 |
| CNS Sarcoma | Central Nervous System Sarcoma | ALIAS | 0.90 |
| Unclassified Tumor, Malignant | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (5)
- label
- CNS Sarcoma
- description
- Patients diagnosed with Central nervous system (CNS) sarcomas
- label
- BCOR-altered
- description
- Patients diagnosed with tumors characterized by alterations in the BCOR gene.
- label
- Astroblastoma/MN-1- altered
- description
- Patients diagnosed with Astroblastomas/MN-1 alterations
- label
- Unclassifiable tumors
- description
- Patients diagnosed with histologically ambiguous tumors or tumors that fail to classify with the current diagnostic methods.
- label
- Other Rare Brain tumors
- description
- Patients diagnosed with other rare brain tumors that do not meet the criteria for cohorts 1-4.
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with a known or suspected CNS Sarcoma. * Patients with a known or suspected BCOR-altered brain tumor * Patients with a known or suspected Astroblastoma/NM-1 altered brain tumor * Patients with known or suspected histologically ambiguous/unclassifiable brain tumor * Patients with a known or suspected rare brain tumor. * Signed informed consent by patient/ parent or guardian (assent where applicable) to participate in the study. Exclusion Criteria: * The patient has an extra-CNS primary tumor. * The patient is older than 46 years of age at diagnosis. * The patient or family is not willing to participate or does not sign informed consent.
References
Publications (0)
Data not yet available
No reference posted for this study.