Clinical trial · Observational
Microscopy Imaging of Whole-mount Stained Human Tissues
Microscopy Imaging of Whole-mount Stained Human Tissues: Development of an Imaging Platform for Intraoperative Tumor Margin Delineation
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to develop an imaging platform for intraoperative tumor margin delineation in 250 cases of tumor-suffered patients. The main questions it aims to answer are: • to develop the protocol of rapid assessment of surgical specimens without need for fixation, embedding, and cryosectioning required for conventional histopathology. Participants will provide a small piece of their surgical specimens from tumor removal surgery . If there is a comparison group: Researchers will compare normal specimens to see if we can observe the difference.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tumor, Brain | Brain Neoplasm | ALIAS | 0.90 |
| Tumor, Breast | Breast Neoplasm | ALIAS | 0.90 |
| Tumor Skin | Skin Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- The assessment between tumor cases and control cases
- timeFrame
- 5 years
- description
- Do comparison with images acquired by our microscopy (with the whole-mount staining method) and bright field microscopy (with standard FFPE method) and do assessment to interpret tumor characteristics
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients who are more than 20 years old. 2. Diagnosed as patients suffered by skin tumor, brain tumor and breast tumor. Exclusion Criteria: 1. Patients who can't speak and communicate with others. 2. Patients who can't make eventual and exact pathological assessment for his/her diseases. 3. Patients who only can fit for slicing tumor. 4. Removed tissues which obviously vary after severe ray radiation under microscopy observation. 5. Diameter of tumors are under 1 centimeter. 6. Breast carcinoma in situ.
References
Publications (0)
Data not yet available