Clinical trial · Observational
Transanal Versus Laparoscopic Total Mesorectal Excision: a Cohort
Transanal Versus Laparoscopic Total Mesorectal Excision: a Prospective Observational Cohort
NCT05682794CI-TRIAL-00063199completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study was to compare the long-term oncology outcomes and specimen quality of taTME and laTME in the treatment of middle and low rectal cancer by a large sample cohort. At the same time, the local recurrence following a primary rectal cancer resection was analyzed to respond to the concerns about the event of the national suspension for TaTME due to the high local recurrence rate in Norway.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| transanal total mesorectal excision | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- taTME
- description
- patients who underwent transanal total mesorectal excision
- interventionNames
- Procedure: transanal total mesorectal excision
- label
- laTME
- description
- patients who underwent laparoscopic total mesorectal excision
Primary outcomes (2)
- measure
- Overall survival rate
- timeFrame
- 5 years after the surgery
- measure
- disease-free survival ratev
- timeFrame
- 5 years after the surgery
Secondary outcomes (5)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age between 18 and 80 years old 2. Confirmed rectal adenocarcinoma cancer pathologically 3. Tumor location ≦ 12 cm from the anal margin 4. Willing and able to provide written informed consent for participation in this study Exclusion Criteria: 1. Distant metastasis before surgery 2. More than one colorectal tumor at diagnosis 3. Familial adenomatous polyposis 4. Recurrent rectal cancer 5. Undergo transanal minimally invasive surgery 6. Undergo palliative treatment 7. Undergo emergency surgery
References
Publications (1)
- DERIVEDLi Z, Liu H, Luo S, Hou Y, Zhou Y, Zheng X, Zhang X, Huang L, Zeng Z, Kang L. Long-term oncological outcomes of transanal versus laparoscopic total mesorectal excision for mid-low rectal cancer: a retrospective analysis of 2502 patients. Int J Surg. 2024 Mar 1;110(3):1611-1619. doi: 10.1097/JS9.0000000000000992. PMID 38091943