Clinical trial · Interventional
Comparison of Needlescopic vs. Conventional Laparoscopic Adrenalectomy for Tumor Less Than 4 cm
Prospective Randomized Comparison of Needlescopic Versus Conventional Laparoscopic Adrenalectomy for Unilateral Adrenal Tumors Less Than 4 cm in Diameter Among Patients With Primary Aldosteronism
NCT05675124CI-TRIAL-00063093not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigator conduct a randomized clinical trial for the needlescopic and conventional laparoscopic adrenalectomy to assess whether mini laparoscopic adrenalectomy is better than conventional laparoscopic adrenalectomy in terms of pain, complication rate , and wound cosmetics
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Post Operative Pain, Acute | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| conventional laparoscopic adrenalectomy | Device | — | UNRESOLVED |
| Needlescopic laparoscopic adrenalectomy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Needlescopic laparoscopic adrenalectomy
- description
- Needlescopic laparoscopic surgery refers to the use of instruments with a diameter of less than or equal to 3 mm for laparoscopic surgery.
- interventionNames
- Device: Needlescopic laparoscopic adrenalectomy
- type
- ACTIVE_COMPARATOR
- label
- conventional laparoscopic adrenalectomy
- description
- a 12 mm camera port ,and two additional (left anterior axillary line and left midclavicular line; for left tumors) or three additional(right anterior axillary line, right midclavicular line, and subxiphoid; for right tumors) 5 mm working ports along the ipsilateral subcostal were created regionally.
- interventionNames
- Device: conventional laparoscopic adrenalectomy
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Over the age of 20 years old. 2. Primary aldosteronism with unilateral adrenal lesions smaller than 4 cm 3. Indications for laparoscopic surgery. 4. Informed consent Exclusion Criteria: 1. Over 80 years old 2. Suspected adrenal malignancy or pheochromocytoma 3. Other concurrent surgery 4. Patients who underwent bilateral adrenal tumor resection at the same time 5. History of peritonitis or having undergoing major ipsilateral abdominal surgery. 6. American Society of Anesthesiologists (ASA) Class III or IV (with severe cardiovascular disease, uncontrolled hypertension, diabetes, chronic pulmonary obstructive pulmonary disease, morbid obesity (BMI \> 40), dialysis patients, myocardial infarction, stroke, coronary artery disease, liver or coagulation dysfunction, etc.) 7. Opioid addiction 8. Patient have side effects from taking of acetaminophen, celecoxib or opioids 9. Acute intoxication of alcohol, sleep aids, anesthetics, centrally acting analgesics, opium or psychotropic drugs has occurred. 10. Patients using monoamine oxidase inhibitors (MAOIs) concurrently or within the past 14 days. 11. Patients with chronic pain or respiratory depression (such as chronic obstructive pulmonary disease) 12. Pregnancy
References
Publications (2)
- BACKGROUNDLiao CH, Lai MK, Li HY, Chen SC, Chueh SC. Laparoscopic adrenalectomy using needlescopic instruments for adrenal tumors less than 5cm in 112 cases. Eur Urol. 2008 Sep;54(3):640-6. doi: 10.1016/j.eururo.2007.12.028. Epub 2007 Dec 26. PMID 18164803
- BACKGROUNDChueh SC, Chen J, Chen SC, Liao CH, Lai MK. Clipless laparoscopic adrenalectomy with needlescopic instruments. J Urol. 2002 Jan;167(1):39-42; discussion 42-3. doi: 10.1016/s0022-5347(05)65378-5. PMID 11743271