Clinical trial · Observational
Treatment Outcomes of Advanced Neoplasia in IBD
Endoscopic and Surgical Treatment Outcomes of Colitis-associated Advanced Neoplasia: a Multicenter Cohort Study
NCT05674773CI-TRIAL-00063049unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this study, we aimed to (1) compare cumulative incidences of synchronous and metachronous colorectal neoplasia as well as mortality following AN in CD and UC patients who underwent proctocolectomy, (sub)total colectomy, partial colectomy or endoscopic resection, and (2) to determine factors associated with AN treatment choice.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Inflammatory Bowel Diseases | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic or surgical resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- IBD patients with advanced neoplasia
- description
- IBD patients with advanced neoplasia (high-grade dysplasia or colorectal cancer) treated with: * proctocolectomy * (sub)total colectomy * partial colectomy * endoscopic resection
- interventionNames
- Procedure: Endoscopic or surgical resection
Primary outcomes (2)
- measure
- Synchronous
- timeFrame
- up to 6 months
- description
- defined as co-existence of two or more neoplastic colorectal lesions detected in the initial resection specimen or up to 6 months after treatment of the index lesion, categorized in (a) any neoplasia (independent of grade) and (b) only AN
- measure
- Metachronous (advanced) neoplasia
- timeFrame
- up to 30 years
- description
- defined as colorectal neoplasia detected \>6 months after treatment of index AN, categorized in (a) any neoplasia (independent of grade) and (b) only AN, including the impact of IBD type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * IBD (ulcerative colitis (UC), CD or IBD-unclassified (IBD-U)) * Histological diagnosis of colorectal AN * Available treatment data Exclusion Criteria: * Familial CRC syndrome * AN prior to IBD diagnosis
References
Publications (0)
Data not yet available
No reference posted for this study.