Clinical trial · Interventional
Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy
Application of Individualized Positive End-expiratory Pressure Using Electrical Impedance Tomography (EIT) in Patients Undergoing Robot Assisted Laparoscopic Prostatectomy : a Randomized Controlled Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Steep trendelenburg posture or pneumoperitoneum for surgery causes ventilation problems during surgery, so finding a way to overcome is a challenging task for anesthesiologists. In this study, for patients undergoing robot assisted laparoscopic prostatectomy under general anesthesia, anesthesia is going to perform by applying conventional positive end-expiratory pressure (PEEP 5cmH2O) or individually determined positive end-expiratory pressure values for each patient using electrical impedance tomography. We plan to compare intraoperative ventilation through arterial blood gas analysis to find out the way to improve intraoperative ventilation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| conventional PEEP | Device | — | UNRESOLVED |
| optimized PEEP | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- conventional PEEP
- description
- Apply of PEEP 5
- interventionNames
- Device: conventional PEEP
- type
- ACTIVE_COMPARATOR
- label
- optimized PEEP
- description
- Apply of optimized PEEP derived using EIT (airtom®)
- interventionNames
- Device: optimized PEEP
Primary outcomes (1)
- measure
- PaO2/FiO2
- timeFrame
- end of surgery (before extubation)
- description
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. 20 - 70 years of age who are scheduled for robotic assisted laparoscopic prostatectomy at the Department of Urology, Gangnam Severance Hospital, 2. ASA-PS (American Society of Anesthesiology Body Rating) I-IlI, 3. Patients with a BMI of 35 kg/m2 or less Exclusion Criteria: 1. Patients with lung disease 2. BMI \>35kg/m2 3. Patients for whom positive end-tidal pressure cannot be applied (large bullae, severe cardiac disease) 4. patient refusal
References
Publications (0)
Data not yet available