Clinical trial · Observational
Extended Resection After Positive Intraoperative Pathology in Gastric Cancer Surgery
Extension of Resection After Positive Intraoperative Pathology During Surgery of Gastric and Gastroesophageal Junction Adenocarcinoma
NCT05663450CI-TRIAL-00062854completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Of 737 consecutive patients undergoing (sub)total gastrectomy for gastric or GEJ adenocarcinoma, 679 cases with curative intent surgery between 05/1996 and 03/2019 were included. Patients were categorized into: i) R0 without further resection (direct R0), ii) R0 after positive IOC and extension of resection (converted R0) and iii) R1.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (3)
- label
- patients with direct R0 (in primary intraoperative pathology consultation)
- description
- patients undergoing (sub)total gastrectomy for gastric or GEJ adenocarcinoma with R0 without further resection (direct R0)
- label
- patients with converted R0 (in second intraoperative pathology consultation)
- description
- patients undergoing (sub)total gastrectomy for gastric or GEJ adenocarcinoma with R0 after positive IOC and extension of resection (converted R0)
- label
- patients with remaining R1 (after final intraoperative pathology consultation)
- description
- patients undergoing (sub)total gastrectomy for gastric or GEJ adenocarcinoma with R1 resection.
Primary outcomes (1)
- measure
- Rate of R1-resection during oncologic surgery
- timeFrame
- intraoperative pathology
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 59 Years
- Maximum age
- 66 Years
Show eligibility criteria text
Inclusion Criteria: * older than 18 years * tumor resection via total gastrectomy and subtotal esophagectomy Exclusion Criteria: * no additional other solid or hematological neoplasias in the medical history * pregnancy * surgical procedures in palliative intention
References
Publications (1)
- DERIVEDPlum PS, Barutcu AG, Pamuk A, Mallmann C, Chon SH, Chiapponi C, Dubbers M, Hellmich M, Moenig SP, Quaas A, Hoelscher AH, Bruns CJ, Alakus H. Extension of resection after positive intraoperative pathology during surgery for gastric and gastroesophageal junction adenocarcinoma: a retrospective cohort study. Int J Surg. 2023 Aug 1;109(8):2324-2333. doi: 10.1097/JS9.0000000000000484. PMID 37222663