Clinical trial · Interventional
Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis
Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis Management in Head and Neck Cancer Patients: A Randomized Controlled Study
NCT05648682CI-TRIAL-00062660completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study was conducted to compare the effectiveness of thyme honey, saline and sodium bicarbonate solution in the management of oral mucositis in patients with head and neck cancer receiving radiotherapy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancers | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Oral Mucositis | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Control | Other | — | UNRESOLVED |
| Salin | Other | — | UNRESOLVED |
| Sodium bicarbonate | Other | — | UNRESOLVED |
| Thyme honey | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Saline
- description
- The patients in the group gargling with saline were given in a 500 ml bottle at each visit for one week of use. Patients were told that they should gargle using approximately two tablespoons of the solution given for each usage.
- interventionNames
- Other: Salin
- type
- EXPERIMENTAL
- label
- Sodium Bicarbonate
- description
- The sodium bicarbonate solution prepared by the researcher by mixing one teaspoon of baking soda (4.5 grams) into 500 ml of distilled water by the researcher was given to the patients in the group gargling with sodium bicarbonate for a one-week use at each interview. Patients were told that they should gargle using approximately two tablespoons of the solution given for each usage.
- interventionNames
- Other: Sodium bicarbonate
- type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Primary diagnosis is head and neck cancer * To be receiving radiotherapy at a dose of 50-60 Gy in the oral cavity * Not be metastatic * OM grade 1 (according to NCI-CTCAE v4.03) * Be 18 years or older * Volunteer to participate in the study * Speak Turkish Exclusion Criteria: * Have an autoimmune disease * Have dental disease * Using dentures * Being allergic to thyme honey * Refusing to participate in the research * To have received radiotherapy treatment in the 6-month period before the start of the study Criteria for terminating the study * The patient's desire to leave the study * Continuing the treatment in another city * Interruption or termination of radiotherapy treatment * Patient's death
References
Publications (0)
Data not yet available
No reference posted for this study.