Clinical trial · Observational
Lung Cancer Screening in Family Members and Peers of Lung Cancer Patients: a Prospective Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Lung cancer screening of active or former heavy smokers with yearly low-dose CT allows for earlier diagnosis and better lung cancer survival. Risk of developing lung cancer is higher among family members and close contacts of lung cancer patients, because of shared genetics, environment and life habits like smoking. The investigators want to engage lung cancer patients to refer their family members and close contacts for lung cancer screening, and evaluate if this referred population have higher risk of lung cancer than the population referred by their family doctors.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Lung Cancer Screening | — | UNRESOLVED | — |
| Patient Empowerment | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Lung cancer patient
- description
- Lung cancer patients or lung cancer survivors willing to refer close contacts for lung cancer screening
- label
- Referred participants
- description
- Participants referred to the study by close contacts living with lung cancer.
Primary outcomes (2)
- measure
- Mean number of referrals for lung cancer screening per participants
- timeFrame
- 2 weeks post inclusion
- description
- Mean number of referrals for lung cancer screening per participants: lung cancer participants will refer contacts directly on the REDCap questionnaire at enrollment. They will be contacted a second time 2 weeks after enrollment and asked if they referred additional people in their entourage for lung cancer screening.
- measure
- Mean PLCOm2012 risk prediction model score among referred participants
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Lung cancer patients: Inclusion Criteria: * \> 18 years old * Current or former lung cancer patient Exclusion Criteria: none Referred participants Inclusion criteria: \>18 years old Exclusion criteria: Personal history of lung cancer.
References
Publications (1)
- DERIVEDPitrou I, Petrangelo A, Besson C, Pepe C, Waschke AH, Agulnik J, Gonzalez AV, Ezer N. Lung Cancer Screening in Family Members and Peers of Patients With Lung Cancer: Protocol for a Prospective Cohort Study. JMIR Res Protoc. 2025 Mar 28;14:e58529. doi: 10.2196/58529. PMID 40153794