Clinical trial · Observational
Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal Snapshot
Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal Snapshot-An International, Multi-centre Study of Emergency Presentations of Colorectal Cancer
NCT05641129CI-TRIAL-00074130APOLLOcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
APOLLO (Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal snapshot) is an international, multi-centre, prospective observational study which will address this need and aims to describe the operative and non-operative management of emergency presentations of colon and rectal cancer in an international cohort.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Main Cohort
- description
- Consecutive adult patients (≥18 years of age) presenting acutely (i.e. unplanned and non-elective presentation to hospital for urgent or emergency reasons) for symptoms of known or unknown colorectal cancer assessed by hospital surgical teams. Patients should be included regardless of operative or non-operative management, and curative or palliative intent.
Primary outcomes (1)
- measure
- Primary outcome
- timeFrame
- 90-day
- description
- Mortality since day of presentation
Secondary outcomes (9)
- measure
- Secondary outcome 1
- timeFrame
- 30-day
- description
- Inpatient mortality, mortality since day of presentation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient pathology: Patients admitted to the hospital acutely with primary colon AND/OR rectal adenocarcinoma and referred to general/colorectal surgical departments: * Patients who are operated on for curative/palliative treatment of colorectal cancer * Patients who are referred to general surgery for assessment (irrespective of if they proceed to surgery) * New diagnoses of colorectal cancer * Extent of cancer: All patients including extra-abdominal metastatic, intra-abdominal metastatic and non-metastatic disease * Known cancer: Patients presenting for the first time with colorectal cancer AND/OR known colorectal cancer diagnosis with progression of disease. i.e. obstruction of known colorectal cancer * Patient presentation: Symptomatic presentation of colorectal cancer i.e. large bowel obstruction, haemorrhage, perforation Exclusion Criteria: * Presenting for side effects of cancer treatment * Patients with secondary cancers * Previously included in the study
References
Publications (1)
- DERIVEDEuroSurg Collaborative and STARSurg Collaborative. Global Use and Outcomes of Endoscopic Stenting in Acute Malignant Left-Sided Colonic Obstruction: A Secondary Analysis of APOLLO, An International, Prospective Cohort Study. Dis Colon Rectum. 2025 Dec 1;68(12):1458-1467. doi: 10.1097/DCR.0000000000003960. Epub 2025 Oct 10. PMID 41070782