Clinical trial · Interventional
Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment
Precision Approaches to Lung Cancer Screening and Smoking Cessation Treatment in Primary Care
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 18, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260918-000001
Summary
Brief summary (as posted)
This trial tests the effects of two versions of RiskProfile, a clinically-informed and a genetically-informed version of a patient-specific risk feedback tool, in comparison to usual care, on lung cancer screening and tobacco treatment. The trial assesses the multilevel effects of these precision risk feedback tools on the likelihood of clinicians to order lung cancer screening and tobacco treatment and of their patients to utilize these cancer prevention interventions.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Smoking | — | UNRESOLVED | — |
| Smoking Cessation | — | UNRESOLVED | — |
| Tobacco Use Cessation | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| RiskProfile-Clin | Behavioral | — | UNRESOLVED |
| RiskProfile-Gen | Behavioral | — | UNRESOLVED |
| Usual Care | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Usual Care
- description
- Annual lung cancer screening with low-dose computed tomography (LDCT) is currently recommended in the U.S. for at-risk patients. Tobacco treatment and cessation is recommended for patients who smoke.
- interventionNames
- Behavioral: Usual Care
- type
- EXPERIMENTAL
- label
- RiskProfile-Clin
- description
- RiskProfile-Clin is a clinically-informed risk feedback tool to activate cancer risk-reducing behaviors.
- interventionNames
- Behavioral: RiskProfile-Clin
- type
- EXPERIMENTAL
- label
- RiskProfile-Gen
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: CLINICIANS: \- Primary care clinician with active caseload in participating clinics PATIENTS: * Patient of participating primary care clinician * Lung cancer screening naïve * Between 50 to 80 years of age, inclusive * Current or former smokers * Pack years ≥ 20 * English-speaking Exclusion Criteria: PATIENTS: * Lung cancer diagnosis * Current order placed for lung cancer screening
References
Publications (0)
Data not yet available