Clinical trial · Interventional
Effect of Natural Compounds on the Severity of HPV-induced Cervical Lesions
NCT05625308CI-TRIAL-00062853completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To test the efficacy of a newly-commercialized formula, 40 HPV-positive women displaying chronic cervicitis, mild dysplasia or moderate dysplasia. Women in the study group took one tablet per day containing 200 mg of EGCG, 400 mcg of Folic Acid, 1 mg of Vitamin B12 and 50 mg of Hyaluronic Acid for twelve weeks. Women in the control group received no treatment.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervix Lesion | — | UNRESOLVED | — |
| Papilloma | Papilloma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Epigallocatechin gallate, Folic acid, Vitamin B12, and Hyaluronic Acid | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Co-treatment with EGCG, FA, B12, and HA
- description
- One tablet per day containing 200 mg of EGCG, 400 mcg of Folic Acid, 1 mg of Vitamin B12 and 50 mg of Hyaluronic Acid for twelve weeks.
- interventionNames
- Dietary Supplement: Epigallocatechin gallate, Folic acid, Vitamin B12, and Hyaluronic Acid
- type
- NO_INTERVENTION
- label
- Control
- description
- Untreated women.
Primary outcomes (1)
- measure
- Regression of cervical lesions
- timeFrame
- 12 weeks
- description
- The actual outcome was to measure the rate of regression of the lesions, from moderate to mild, from mild to none.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria: * HPV infections * Occurrence of low-grade cervical lesions Exclusion Criteria: * Diagnosis of malignancy or severe cervical lesions * Concurrent uterine pathologies * Pregnancy or intended to seek pregnancy in the next three months * Cancer
References
Publications (0)
Data not yet available
No reference posted for this study.