Clinical trial · Interventional
StableEyes With Active Neurofeedback
StableEyes With Active Neurophysiological Feedback
NCT05622344CI-TRIAL-00097074SWANrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 9, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260909-000002
Summary
Brief summary (as posted)
The investigators have developed a self-administered rehabilitation tool that incrementally guides the user to increase head motion to mitigate motion sickness and enhance postural recovery following centrifugation or unilateral vestibular nerve deafferentation surgery.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Motion Sickness | — | UNRESOLVED | — |
| Space Motion Sickness | — | UNRESOLVED | — |
| Vestibular Disorder | — | UNRESOLVED | — |
| Vestibular Schwannoma | Vestibular Schwannoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| SWAN | Device | — | UNRESOLVED |
| Traditional Therapy | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Traditional Vestibular Physical Therapy (VPT) JHU
- description
- Subjects that have had their eighth cranial nerve resected will receive traditional vestibular rehabilitation exercises at Johns Hopkins University (JHU) site.
- interventionNames
- Behavioral: Traditional Therapy
- type
- EXPERIMENTAL
- label
- SWAN VPT JHU
- description
- Subjects that have had their eighth cranial nerve resected will receive the automated vestibular rehabilitation method
- interventionNames
- Device: SWAN
- type
- EXPERIMENTAL
- label
- SWAN Motion Sick Dayton
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Provision of signed and dated informed consent form 2. Stated willingness to comply with all study procedures and availability for the duration of the study 3. In good general health as evidenced by medical history or diagnosed with unilateral vestibular schwannoma 4. Willing to adhere to the SWAN and/or vestibular rehabilitation regimen Exclusion Criteria: 1. Current use of anti-nausea medication 2. Presence of cervical spine pathology that limits head motion to \< 30 degrees in the horizontal or vertical plane (i.e. degenerative disc disease, rheumatoid arthritis) 3. Any orthopedic pathology that prevents walking or standing independently (i.e. recent surgery) 4. Legal blindness (20/200 or worse visual acuity) 5. Treatment using a motion sickness investigational drug or other motion sickness behavioral intervention within 30 days
References
Publications (1)
- BACKGROUNDTodd CJ, Schubert MC, Rinaudo CN, Migliaccio AA. Unidirectional Vertical Vestibuloocular Reflex Adaptation in Humans Using 1D and 2D Scenes. Otol Neurotol. 2022 Oct 1;43(9):e1039-e1044. doi: 10.1097/MAO.0000000000003684. Epub 2022 Sep 9. PMID 36075099